Basic information of MS4A1 :

Official Symbol of Gene	MS4A1
Species	Homo sapiens
Entrez Gene ID	931
Official Full Name	membrane spanning 4-domains A1
Also known as	B1; S7; Bp35; CD20; FMC7; CVID5; LEU-16
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000156738 MIM:112210; AllianceGenome:HGNC:7315
Map Location	11q12.2
Drug	rituximab
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	RRMS
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	21155688
Year	2011
Title	Antibodies against CD20 (rituximab) for treating multiple sclerosis: US20100233121

Results of multiple sclerosis :

Result	Future studies will involve the administration of antibodies against CD20 by gene therapy and studying and characterizing the administration of multiples drugs, in combination rituximab, for treating MS.
Mechanism/pathway	Rituximab depletes peripheral B cells and reduces the level of B cells in the cerebrospinal fluid of patients with relapsing-remitting MS.