Basic information of ABCG2 :

Official Symbol of Gene	ABCG2
Species	Homo sapiens
Entrez Gene ID	9429
Official Full Name	ATP binding cassette subfamily G member 2 (Junior blood group)
Also known as	MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; GOUT1; MXR-1; CDw338; CDw388; UAQTL1; EST157481
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000118777 MIM:603756; AllianceGenome:HGNC:74
Map Location	4q22.1
Drug	mitoxantrone
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	n=121
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	19605531
Year	2009
Title	ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis

Results of multiple sclerosis :

Result	In conclusion, SNPs in ABC-transporter genes may serve as pharmacogenetic markers associated with clinical response to MX therapy in multiple sclerosis.
Mechanism/pathway	ATP-binding cassette-transporters ABCB1 and ABCG2 represent multi-drug resistance mechanisms involved in active cellular MX efflux.