Basic information of Abcb1b :

Official Symbol of Gene	Abcb1b
Species	Mus musculus
Entrez Gene ID	18669
Official Full Name	ATP-binding cassette, sub-family B (MDR/TAP), member 1B
Also known as	mdr; Mdr1; Pgy1; Abcb1; Mdr1b; Pgy-1
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000028970 AllianceGenome:MGI:97568
Map Location	5 A1; 5 3.43 Cm
Drug	mitoxantrone
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	N/A
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	19605531
Year	2009
Title	ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis

Results of multiple sclerosis :

Result	In conclusion, SNPs in ABC-transporter genes may serve as pharmacogenetic markers associated with clinical response to MX therapy in multiple sclerosis.
Mechanism/pathway	ATP-binding cassette-transporters ABCB1 and ABCG2 represent multi-drug resistance mechanisms involved in active cellular MX efflux.