Basic information of Abcg2 :

Official Symbol of Gene	Abcg2
Species	Mus musculus
Entrez Gene ID	26357
Official Full Name	ATP binding cassette subfamily G member 2 (Junior blood group)
Also known as	MXR; ABCP; BCRP; MXR1; ABC15; Bcrp1
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000029802 AllianceGenome:MGI:1347061
Map Location	6 B3; 6 27.82 cM
Drug	mitoxantrone
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	N/A
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	19605531
Year	2009
Title	ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis

Results of multiple sclerosis :

Result	In conclusion, SNPs in ABC-transporter genes may serve as pharmacogenetic markers associated with clinical response to MX therapy in multiple sclerosis.
Mechanism/pathway	ATP-binding cassette-transporters ABCB1 and ABCG2 represent multi-drug resistance mechanisms involved in active cellular MX efflux.