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Basic information of MIR26A1 :

Official Symbol of Gene MIR26A1
Species Homo sapiens
Entrez Gene ID 407015
Official Full Name microRNA 26a-1
Also known as MIR26A; MIRN26A1; mir-26a-1
Gene Type ncRNA
dbXrefs Ensembl:ENSG00000199075 MIM:612151; miRBase:MI0000083; AllianceGenome:HGNC:31610
Map Location 3p22.2
Drug IFN-β therapy
Interaction Type activator

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 24885345
Year 2014
Title Small non-coding RNA signature in multiple sclerosis patients after treatment with interferon-β

Results of multiple sclerosis :

Result MiR-26a-5p expression was significantly higher in IFN-β treated RRMS patients at 3 months treatment, keeping quite stable at 6 months treatments.
Mechanism/pathway Functional annotations of hsa-mir-26a-5p targets revealed that several genes were implicated in Glutamate Receptor Signaling pathway, which is notoriously altered in neurodegenerative diseases as MS.