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Basic information of Cnr1 :

Official Symbol of Gene Cnr1
Species Mus musculus
Entrez Gene ID 12801
Official Full Name cannabinoid receptor 1 (brain)
Also known as CB1; CB-R; CB1A; CB1B; CB1R
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000044288 AllianceGenome:MGI:104615
Map Location 4 A5; 4 16.28 Cm
Drug cannabinoids
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent Biozzi ABH and ABH mice lacking the CB1 receptor (Cnr1) gene
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 17220914
Year 2007
Title Control of Spasticity in a Multiple Sclerosis Model is mediated by CB1, not CB2, Cannabinoid Receptors

Results of multiple sclerosis :

Result Gene knockout technology provides an important tool in target validation and indicates that the CB1 receptor is the main cannabinoid target for an anti-spastic effect.
Mechanism/pathway N/A