Basic information of CD80 :

Official Symbol of Gene	CD80
Species	Homo sapiens
Entrez Gene ID	941
Official Full Name	CD80 molecule
Also known as	B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000121594 MIM:112203; AllianceGenome:HGNC:1700
Map Location	3q13.33
Drug	Cladribine treatment
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	N/A
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	35734180
Year	2022
Title	Cladribine Treatment for MS Preserves the Differentiative Capacity of Subsequently Generated Monocytes, Whereas Its Administration In Vitro Acutely Influences Monocyte Differentiation but Not Microglial Activation

Results of multiple sclerosis :

Result	In addition, MDMs treated with cladribine showed increased expression of costimulatory molecules CD80 and CD40, as well as expression of anti-inflammatory, pro-trophic genes IL10 and MERTK, depending on the differentiation condition. Cladribine treatment in vitro.
Mechanism/pathway	N/A