Basic information of CD40 :

Official Symbol of Gene	CD40
Species	Mus musculus
Entrez Gene ID	21939
Official Full Name	CD40 antigen
Also known as	IGM; p50; Bp50; GP39; IMD3; TRAP; HIGM1; T-BAM; Tnfrsf5
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000017652 AllianceGenome:MGI:88336
Map Location	2 H3; 2 85.38 cM
Drug	IFN-b treatment
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	C57BL/6J mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	16571771
Year	2006
Title	IFN-beta-induced SOCS-1 negatively regulates CD40 gene expression in macrophages and microglia

Results of multiple sclerosis :

Result	In these cells, IFN--induced CD40 mRNA expression was attenuated compared to wild-type (WT) microglia.
Mechanism/pathway	IFN-beta-induced SOCS-1 negatively regulates CD40 gene expression in macrophages and microglia