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Basic information of IL10 :

Official Symbol of Gene IL10
Species Homo sapiens
Entrez Gene ID 3586
Official Full Name interleukin 10
Also known as CSIF; TGIF; GVHDS; IL-10; IL10A
Gene Type protein coding
dbXrefs Ensembl:ENSG00000136634 MIM:124092; AllianceGenome:HGNC:5962
Map Location 1q32.1
Drug Cladribine treatment
Interaction Type activator

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 35734180
Year 2022
Title Cladribine Treatment for MS Preserves the Differentiative Capacity of Subsequently Generated Monocytes, Whereas Its Administration In Vitro Acutely Influences Monocyte Differentiation but Not Microglial Activation

Results of multiple sclerosis :

Result In addition, MDMs treated with cladribine showed increased expression of costimulatory molecules CD80 and CD40, as well as expression of anti-inflammatory, pro-trophic genes IL10 and MERTK, depending on the differentiation condition. Cladribine treatment in vitro.
Mechanism/pathway anti-inflammatory cytokine