Basic information of Ifnk :

Official Symbol of Gene	Ifnk
Species	Mus musculus
Entrez Gene ID	387510
Official Full Name	interferon kappa
Also known as	If1fa
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000042993 AllianceGenome:MGI:2683287
Map Location	4; 4 A5
Drug	pMxkIFNkβ
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	spinal cords
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	28257578
Year	2017
Title	Amelioration of experimental autoimmune encephalomyelitis in mice by interferon-beta gene therapy, using a long-term expression plasmid vector

Results of multiple sclerosis :

Result	These results indicate that IFNkβ transgene expression by single administration of the pMxkIFNkβ can be an effective longkterm treatment for MS
Mechanism/pathway	Gene transfer of pMxcIFNcβ reduced the severity of EAE. The EAE mice received a single administration of plasmid DNA by hydrodynamic injection on day 7 after the initial immunization with MOG35k55. pMxkgLuc, a plasmid vector encoding the reporter protein gLuc, was used as control vector.