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Basic information of Ifnb1 :

Official Symbol of Gene Ifnb1
Species Mus musculus
Entrez Gene ID 15977
Official Full Name interferon beta 1, fibroblast
Also known as Ifb; IFNB; If1da1; IFN-beta
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000048806 AllianceGenome:MGI:107657
Map Location 4 C4; 4 41.91 cM
Drug gal-9
Interaction Type activator

Sample information of multiple sclerosis:

Descent peripheral blood
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 29217470
Year 2017
Title Safe and effective interferon-beta gene therapy for the treatment of multiple sclerosis by regulating biological activity through the design of interferon-beta-galectin-9 fusion proteins

Results of multiple sclerosis :

Result These results indicate that gene therapy using IFN-β-gal-9 fusion proteins is expected to be safe and effective for the treatment of MS
Mechanism/pathway The IFN-β-gal-9 fusion proteins showed less IFN-β biological activity on non-T cells than IFN-β alone