Basic information of MERIK :

Official Symbol of Gene	MERIK
Species	Homo sapiens
Entrez Gene ID	10461
Official Full Name	MER proto-oncogene, tyrosine kinase
Also known as	MER; RP38; c-Eyk; c-mer; Tyro12
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000153208 MIM:604705; AllianceGenome:HGNC:7027
Map Location	2q13
Drug	Cladribine treatment
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	N/A
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	35734180
Year	2022
Title	Cladribine Treatment for MS Preserves the Differentiative Capacity of Subsequently Generated Monocytes, Whereas Its Administration In Vitro Acutely Influences Monocyte Differentiation but Not Microglial Activation

Results of multiple sclerosis :

Result	In addition, MDMs treated with cladribine showed increased expression of costimulatory molecules CD80 and CD40, as well as expression of anti-inflammatory, pro-trophic genes IL10 and MERTK, depending on the differentiation condition. Cladribine treatment in vitro.
Mechanism/pathway	the efferocytosis-related receptor