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Basic information of Ifna1 :

Official Symbol of Gene Ifna1
Species Mus musculus
Entrez Gene ID 15962
Official Full Name interferon alpha 1
Also known as Ifa1; If1ai14
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000095498 AllianceGenome:MGI:107668
Map Location 4 C4; 4 42.04 cM
Drug B18R
Interaction Type activator

Sample information of multiple sclerosis:

Descent peripheral blood、peritoneal
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 24811478
Year 2014
Title Short Peptide Type I Interferon Mimetics: Therapeutics for Experimental Allergic Encephalomyelitis, Melanoma, and Viral Infections

Results of multiple sclerosis :

Result The mimetics lack toxic side effects of the parent IFNs and, thus, are a potent therapeutic replacement of IFNs as therapeutics
Mechanism/pathway human IFNa1(152–189), human IFNb(150–187), and ovine IFNt(156–195) are derived from the C-terminus of the parent IFNs and function intracellularly based on the noncanonical model