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Basic information of MX1 :

Official Symbol of Gene MX1
Species Homo sapiens
Entrez Gene ID 4599
Official Full Name MX dynamin like GTPase 1
Also known as MX; MxA; IFI78; IFI-78K; lncMX1-215
Gene Type protein coding
dbXrefs Ensembl:ENSG00000157601 MIM:147150; AllianceGenome:HGNC:7532
Map Location 21q22.3
Drug IFN-β therapy
Interaction Type activator

Sample information of multiple sclerosis:

Descent RRMS
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 34808619
Year 2022
Title The Effect of Interferon-Beta Therapy on T-Helper 17/miR-326 and T-Helper 1/miR-29b-3p Axis in Relapsing-Remitting Multiple Sclerosis Patients

Results of multiple sclerosis :

Result MxA gene expression was significantly induced upon IFN-β therapy in patients with RRMS.
Mechanism/pathway Myxovirus resistance protein 1 (MxA) as one of the main reliable biomarkers for IFN-β bioactivity is measured upon treatment with IFN-β.