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Basic information of BE :

Official Symbol of Gene BE
Species Homo sapiens
Entrez Gene ID 5443
Official Full Name proopiomelanocortin
Also known as LPH; MSH; NPP; POC; ACTH; CLIP; OBAIRH
Gene Type protein coding
dbXrefs Ensembl:ENSG00000115138 MIM:176830; AllianceGenome:HGNC:9201
Map Location 2p23.3
Drug LDN treatment
Interaction Type activator

Sample information of multiple sclerosis:

Descent PPMS
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 18728058
Year 2008
Title A pilot trial of low-dose naltrexone in primary progressive multiple sclerosis

Results of multiple sclerosis :

Result A significant (P < 0.05) increase of BE concentration(mean ± SEM) was measured either at 3 months(63.4 ± 4.8) and 6 months (76.9 ± 3.3) after the beginning of LDN treatment.
Mechanism/pathway BE is a peptide neurotransmitter produced by pituitary and hypothalamic neuronal cells