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Basic information of CD86 :

Official Symbol of Gene CD86
Species Homo sapiens
Entrez Gene ID 942
Official Full Name CD86 molecule
Also known as B70; B7-2; B7.2; LAB72; CD28LG2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000114013 MIM:601020; AllianceGenome:HGNC:1705
Map Location 3q13.33
Drug DMF treatment
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 29106333
Year 2019
Title Monomethyl fumarate treatment impairs maturation of human myeloid dendritic cells and their ability to activate T cells

Results of multiple sclerosis :

Result MMF treatment induced a less mature phenotype of mDCs with reduced expression of major histocompatibility complex class II (MHC-II), co-stimulatory molecules CD86, CD40, CD83, and expression of nuclear factor κB (NF-κB) subunits RELA and RELB.
Mechanism/pathway N/A