Home Details
| Official Symbol of Gene | CD86 |
| Species | Homo sapiens |
| Entrez Gene ID | 942 |
| Official Full Name | CD86 molecule |
| Also known as | B70; B7-2; B7.2; LAB72; CD28LG2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000114013 MIM:601020; AllianceGenome:HGNC:1705 |
| Map Location | 3q13.33 |
| Drug | DMF treatment |
| Interaction Type | inhibitor |
| Descent | N/A |
| Disease | MS |
| Pubmed ID | 29106333 |
| Year | 2019 |
| Title | Monomethyl fumarate treatment impairs maturation of human myeloid dendritic cells and their ability to activate T cells |
| Result | MMF treatment induced a less mature phenotype of mDCs with reduced expression of major histocompatibility complex class II (MHC-II), co-stimulatory molecules CD86, CD40, CD83, and expression of nuclear factor κB (NF-κB) subunits RELA and RELB. |
| Mechanism/pathway | N/A |

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