Basic information of CD40 :

Official Symbol of Gene	CD40
Species	Homo sapiens
Entrez Gene ID	958
Official Full Name	CD40 molecule
Also known as	p50; Bp50; CDW40; TNFRSF5
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000101017 MIM:109535; AllianceGenome:HGNC:11919
Map Location	20q13.12
Drug	DMF treatment
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	N/A
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	29106333
Year	2019
Title	Monomethyl fumarate treatment impairs maturation of human myeloid dendritic cells and their ability to activate T cells

Results of multiple sclerosis :

Result	MMF treatment induced a less mature phenotype of mDCs with reduced expression of major histocompatibility complex class II (MHC-II), co-stimulatory molecules CD86, CD40, CD83, and expression of nuclear factor κB (NF-κB) subunits RELA and RELB.
Mechanism/pathway	N/A