Basic information of RELB :

Official Symbol of Gene	RELB
Species	Homo sapiens
Entrez Gene ID	5971
Official Full Name	RELB proto-oncogene, NF-kB subunit
Also known as	IREL; I-REL; IMD53; REL-B
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000104856 MIM:604758; AllianceGenome:HGNC:9956
Map Location	19q13.32
Drug	DMF treatment
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	N/A
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	29106333
Year	2019
Title	Monomethyl fumarate treatment impairs maturation of human myeloid dendritic cells and their ability to activate T cells

Results of multiple sclerosis :

Result	MMF treatment induced a less mature phenotype of mDCs with reduced expression of major histocompatibility complex class II (MHC-II), co-stimulatory molecules CD86, CD40, CD83, and expression of nuclear factor κB (NF-κB) subunits RELA and RELB.
Mechanism/pathway	N/A