Details

Home Details


Basic information of IL17A :

Official Symbol of Gene IL17A
Species Homo sapiens
Entrez Gene ID 3605
Official Full Name interleukin 17A
Also known as IL17; CTLA8; IL-17; ILA17; CTLA-8; IL-17A
Gene Type protein coding
dbXrefs Ensembl:ENSG00000112115 MIM:603149; AllianceGenome:HGNC:5981
Map Location 6p12.2
Drug MMF treatment
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 29106333
Year 2019
Title Monomethyl fumarate treatment impairs maturation of human myeloid dendritic cells and their ability to activate T cells

Results of multiple sclerosis :

Result T cells co-cultured with MMF-treated mDCs showed reduced proliferation with decreased production of interferon gamma (IFN-γ), interleukin-17 (IL-17), and granulocyte-macrophage colony-stimulating factor (GM-CSF) compared to untreated cells.
Mechanism/pathway N/A