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Basic information of Il4 :

Official Symbol of Gene Il4
Species Mus musculus
Entrez Gene ID 16189
Official Full Name interleukin 4
Also known as Il-4; BSF-1
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000000869 AllianceGenome:MGI:96556
Map Location 11 B1.3; 11 31.97 cM
Drug treated with PBS or AdIF
Interaction Type activator

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 21277028
Year 2011
Title Identification of astrocyte-derived immune suppressor factor that induces apoptosis of autoreactive T cells

Results of multiple sclerosis :

Result Those derived from AdIF-treated mice demonstrated increased IL-4 and suppressed IFN-γ secretion.
Mechanism/pathway The newly discovered molecule AdIF may also render auto reactive T cells susceptible to the induction of apoptotic cell death.