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Basic information of Gfap :

Official Symbol of Gene Gfap
Species Mus musculus
Entrez Gene ID 14580
Official Full Name glial fibrillary acidic protein
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000020932 AllianceGenome:MGI:95697
Map Location 11 E1; 11 66.48 cM
Drug AST treatment
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 25150364
Year 2014
Title Astragalosides from Radix Astragali benefits experimental autoimmune encephalomyelitis in C57BL /6 mice at multiple levels

Results of multiple sclerosis :

Result AST inhibited GFAP mRNA expression.
Mechanism/pathway After AST treatment, the activation of astrocytes and microglia cells was inhibited as the mRNA levels of both GFAP and CD11b were reduced remarkably.