Basic information of Itgam :

Official Symbol of Gene	Itgam
Species	Mus musculus
Entrez Gene ID	16409
Official Full Name	integrin alpha M
Also known as	CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000030786 AllianceGenome:MGI:96607
Map Location	7; 7 F3
Drug	AST treatment
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	C57BL/6 mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	25150364
Year	2014
Title	Astragalosides from Radix Astragali benefits experimental autoimmune encephalomyelitis in C57BL /6 mice at multiple levels

Results of multiple sclerosis :

Result	AST reduced CD11b mRNA expression.
Mechanism/pathway	After AST treatment, the activation of astrocytes and microglia cells was inhibited as the mRNA levels of both GFAP and CD11b were reduced remarkably.