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Basic information of Nos2 :

Official Symbol of Gene Nos2
Species Mus musculus
Entrez Gene ID 18126
Official Full Name nitric oxide synthase 2, inducible
Also known as iNOS; Nos-2; Nos2a; i-NOS; NOS-II; MAC-NOS
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000020826 AllianceGenome:MGI:97361
Map Location 11 B5; 11 46.74 cM
Drug AST treatment
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 25150364
Year 2014
Title Astragalosides from Radix Astragali benefits experimental autoimmune encephalomyelitis in C57BL /6 mice at multiple levels

Results of multiple sclerosis :

Result AST prevented iNOS mRNA expression.
Mechanism/pathway After AST treatment, the activation of astrocytes and microglia cells was inhibited as the mRNA levels of both GFAP and CD11b were reduced remarkably.