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Basic information of Rorc :

Official Symbol of Gene Rorc
Species Mus musculus
Entrez Gene ID 19885
Official Full Name RAR-related orphan receptor gamma
Also known as TOR; Thor; Nr1f3; RORgamma
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000028150 AllianceGenome:MGI:104856
Map Location 3; 3 F2.1
Drug AST treatment
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 25150364
Year 2014
Title Astragalosides from Radix Astragali benefits experimental autoimmune encephalomyelitis in C57BL /6 mice at multiple levels

Results of multiple sclerosis :

Result AST inhibited RORγt mRNA expression.
Mechanism/pathway In our experiments, all of the three transcriptional factors were modulated by AST administra tion at mRNA levels.