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Basic information of Tbx21 :

Official Symbol of Gene Tbx21
Species Mus musculus
Entrez Gene ID 57765
Official Full Name T-box 21
Also known as TBT1; Tbet; Tblym
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000001444 AllianceGenome:MGI:1888984
Map Location 11; 11 D
Drug AST treatment
Interaction Type activator

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 25150364
Year 2014
Title Astragalosides from Radix Astragali benefits experimental autoimmune encephalomyelitis in C57BL /6 mice at multiple levels

Results of multiple sclerosis :

Result AST increased T-bet mRNA expression.
Mechanism/pathway In our experiments, all of the three transcriptional factors were modulated by AST administra tion at mRNA levels.