| PMID:
26575981
|
| Subject&Disease:
Osteosarcoma
|
| Sample:
Tumor tissues; Cell lines (U2OS, MNNG/HOS, etal)
|
| Species:
Homo sapiens
|
| ncRNA Category:
null
|
| ncRNA Symbols:
lncRNA
|
| Accession number:
lncRNA-MALAT1
|
| chromosome Location:
null
|
| Expression pattern:
null
|
| High-throughput experiment methods:
Upregulation
|
| Low-throughput experiment methods:
null
|
| Targets of ncRNA:
RT-PCR
|
| Detection methods for targets:
null
|
| Description the function of ncRNA:
(1) MALAT1 plays an oncogenic role in osteosarcoma. (2) administration of MALAT1 siRNA decreased the protein levels of RhoA and its downstream effectors Rho-associated coiled-coil containing protein kinases (ROCKs).
|
| Year:
2016
|
| Title:
Long noncoding RNA MALAT1 as a potential therapeutic target in osteosarcoma.
|
| External Link:
Ensembl Link
;
HGNC Link
|
