| PMID:
28122633
|
| Subject&Disease:
Bone metastasis (Prostate Cancer)
|
| Sample:
Tumor tissue; Cell line (PC-3, DU145 and PZ-HPV7)
|
| Species:
Homo sapiens/Mus musculus
|
| ncRNA Category:
null
|
| ncRNA Symbols:
miRNA
|
| Accession number:
miR-376c
|
| chromosome Location:
null
|
| Expression pattern:
null
|
| High-throughput experiment methods:
Downregulation
|
| Low-throughput experiment methods:
null
|
| Targets of ncRNA:
RT-PCR,etal
|
| Detection methods for targets:
null
|
| Description the function of ncRNA:
(1) TSP-2 enhances the migration of PCa cells by increasing MMP-2 expression through down-regulation of miR-376c expression. (2) The expression of TSP-2 is correlated with MMP-2 expression and tumor stage in PCa..
|
| Year:
2017
|
| Title:
Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression.
|
| External Link:
Ensembl Link
;
HGNC Link
|
