| PMID:
25912304
|
| Subject&Disease:
Osteosarcoma
|
| Sample:
Tumor tissue; Cell line (Saos-2, MG-63, HOS, U2OS; 143B, etal)
|
| Species:
Homo sapiens
|
| ncRNA Category:
null
|
| ncRNA Symbols:
miRNA
|
| Accession number:
miR-144
|
| chromosome Location:
null
|
| Expression pattern:
null
|
| High-throughput experiment methods:
Downregulation
|
| Low-throughput experiment methods:
null
|
| Targets of ncRNA:
RT-PCR,etal
|
| Detection methods for targets:
ROCK1 and ROCK2
|
| Description the function of ncRNA:
(1) miR-144 suppresses OS progression by directly downregulating ROCK1 and ROCK2 expression. (2) Lowlevel expression of miR-144 was significantly associated with distant metastasis and poor prognosis.
|
| Year:
2015
|
| Title:
MicroRNA-144 suppresses osteosarcoma growth and metastasis by targeting ROCK1 and ROCK2
|
| External Link:
Ensembl Link
;
HGNC Link
|
