| PMID:
21643012
|
| Subject&Disease:
Ewing sarcoma
|
| Sample:
Cell line (A673, etal)
|
| Species:
Homo sapiens
|
| ncRNA Category:
|
| ncRNA Symbols:
miRNA
|
| Accession number:
miR-27a
|
| chromosome Location:
|
| Expression pattern:
|
| High-throughput experiment methods:
Downregulation
|
| Low-throughput experiment methods:
Microarray
|
| Targets of ncRNA:
RT-PCR
|
| Detection methods for targets:
|
| Description the function of ncRNA:
(1) miR-27a negatively regulates IGF-1 expression in Ewing sarcoma. (2) the regulation of IGF-1 protein levels occurs via other mechanisms.
|
| Year:
2011
|
| Title:
A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway
targeting by EWS/Fli1-regulated microRNAs
|
| External Link:
Ensembl Link
;
HGNC Link
|
