| PMID:
22698405
|
| Subject&Disease:
Ewing sarcoma
|
| Sample:
Tumor tissue; Cell line (A673, TC252, STA-ET-8.2, etal)
|
| Species:
Homo sapiens
|
| ncRNA Category:
|
| ncRNA Symbols:
miRNA
|
| Accession number:
miR-143
|
| chromosome Location:
|
| Expression pattern:
|
| High-throughput experiment methods:
Downregulation
|
| Low-throughput experiment methods:
Microarray
|
| Targets of ncRNA:
RT-PCR
|
| Detection methods for targets:
|
| Description the function of ncRNA:
(1) miRNA-143 and miRNA-145 control Ewing sarcoma family tumor (ESFT) cancer stem cell (CSC) self-Renewal and tumorigenicity. (2) miRNA profile of ESFT CSCs is the result of reversible disruption of TARBP2-dependent miRNA maturation.
|
| Year:
2012
|
| Title:
A TARBP2-Dependent miRNA Expression Profile
Underlies Cancer Stem Cell Properties and Provides
Candidate Therapeutic Reagents in Ewing Sarcoma
|
| External Link:
Ensembl Link
;
HGNC Link
|
