| PMID:
24360951
|
| Subject&Disease:
Giant Cell Tumor of Bone
|
| Sample:
Tumor tissue, BMM cells isolated from C57/BL6 mice and GCTSCs isolated from GCT samples
|
| Species:
Homo sapiens/Mus musculus
|
| ncRNA Category:
null
|
| ncRNA Symbols:
miRNA
|
| Accession number:
miR-126-5p
|
| chromosome Location:
null
|
| Expression pattern:
null
|
| High-throughput experiment methods:
Downregulation
|
| Low-throughput experiment methods:
null
|
| Targets of ncRNA:
RT-PCR,etal
|
| Detection methods for targets:
MMP-13
|
| Description the function of ncRNA:
(1) MiR-126-5p was expressed at low level in GCT. (2) MiR-126-5p could negatively regulate MMP-13 expression. (3) MiR-126-5p can regulate OC differentiation and osteolysis formation in GCT.
|
| Year:
2014
|
| Title:
MiR-126-5p regulates osteoclast differentiation and bone resorption in giant cell tumor through inhibition of MMP-13.
|
| External Link:
Ensembl Link
;
HGNC Link
|
