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    RESULT:

PMID: 29051990
Subject&Disease: Spinal chordoma
Sample: Tumor tissue
Species: Homo sapiens
ncRNA Category: null
ncRNA Symbols: miRNA
Accession number: hsa-miR-4652-3p
chromosome Location: null
Expression pattern: null
High-throughput experiment methods: Downregulation
Low-throughput experiment methods: Microarray
Targets of ncRNA: RT-PCR
Detection methods for targets: null
Description the function of ncRNA: (1) MiR-574-3p was identified to potentially regulate PD-L1 expression in chordoma, which inversely correlated with PD-L1. (2) Decreased miR-574-3p level correlated with higher muscle invasion, more severe tumor necrosis and poor patient survival.
Year: 2017
Title: Clinicopathologic implications of CD8+/Foxp3+ ratio and miR-574-3p/PD-L2 axis in spinal chordoma patients
External Link: Ensembl Link ; HGNC Link

 

 

ODNA
Harbin Medical University, China