| PMID:
24967703
|
| Subject&Disease:
Lyme arthritis
|
| Sample:
Joint tissue; Bone marrow-derived macrophages
|
| Species:
Mus musculus
|
| ncRNA Category:
miRNA
|
| ncRNA Symbols:
miR-146a
|
| Accession number:
null
|
| chromosome Location:
null
|
| Expression pattern:
Upregulation
|
| High-throughput experiment methods:
Microarray
|
| Low-throughput experiment methods:
RT-PCR
|
| Targets of ncRNA:
null
|
| Detection methods for targets:
null
|
| Description the function of ncRNA:
miR-146a-mediated regulation of TRAF6 and NF-κB, and downstream targets such as IL-1β, IL-6 and CXCL1, are critical for modulation of Lyme arthritis during chronic infection with B. burgdorferi.
|
| Year:
2014
|
| Title:
MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi.
|
| External Link:
Ensembl Link
;
HGNC Link
|