| PMID:
20675358
|
| Subject&Disease:
Osteoarthritis
|
| Sample:
Chondrocytes
|
| Species:
Rattus norvegicus
|
| ncRNA Category:
miRNA
|
| ncRNA Symbols:
miR-34a
|
| Accession number:
null
|
| chromosome Location:
null
|
| Expression pattern:
Upregulation
|
| High-throughput experiment methods:
null
|
| Low-throughput experiment methods:
null
|
| Targets of ncRNA:
null
|
| Detection methods for targets:
null
|
| Description the function of ncRNA:
Silencing of miR-34a significantly prevented IL-1β-induced down-regulation of Col2a1, as well as IL-1β-induced up-regulation of iNOS. Finally, MiR-34a inhibitor could also reduce TUNEL-positive cells.
|
| Year:
2010
|
| Title:
Silencing microRNA-34a inhibits chondrocyte apoptosis in a rat osteoarthritis model in vitro.
|
| External Link:
Ensembl Link
;
HGNC Link
|
