| PMID:
24572376
|
| Subject&Disease:
Osteoarthritis
|
| Sample:
Chondrocytes
|
| Species:
Homo sapiens/Mus musculus
|
| ncRNA Category:
miRNA
|
| ncRNA Symbols:
miR-24
|
| Accession number:
|
| chromosome Location:
|
| Expression pattern:
Downreguation
|
| High-throughput experiment methods:
|
| Low-throughput experiment methods:
RT-PCR,etal
|
| Targets of ncRNA:
|
| Detection methods for targets:
|
| Description the function of ncRNA:
miR-24 as a negative regulator of p16INK4a. Accordingly, p16INK4a expression increased while miR-24 level was repressed upon IL-1-beta addition, in OA cartilage and during in vitro terminal chondrogenesis.
|
| Year:
2015
|
| Title:
p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis.
|
| External Link:
Ensembl Link
;
HGNC Link
|