| PMID:
26045761
|
| Subject&Disease:
Osteoarthritis
|
| Sample:
Cartilage specimens; Chondrocytes
|
| Species:
Homo sapiens/Rattus norvegicus
|
| ncRNA Category:
miRNA
|
| ncRNA Symbols:
miR-130a
|
| Accession number:
null
|
| chromosome Location:
null
|
| Expression pattern:
Downreguation
|
| High-throughput experiment methods:
null
|
| Low-throughput experiment methods:
RT-PCR,etal
|
| Targets of ncRNA:
null
|
| Detection methods for targets:
null
|
| Description the function of ncRNA:
miR-130a played an important role in regulating the expression of TNF-α in human chondrocytes. iRNA-130a regulated a distinct underlying molecular and pathogenic mechanism of OA by forming a negative feedback loop with TNF-α.
|
| Year:
2015
|
| Title:
Decreased expression of microRNA-130a correlates with TNF-α in the development of osteoarthritis.
|
| External Link:
Ensembl Link
;
HGNC Link
|
