| PMID:
26673737
|
| Subject&Disease:
Osteoarthritis
|
| Sample:
Chondrocytes
|
| Species:
Homo sapiens/Mus musculus
|
| ncRNA Category:
miRNA
|
| ncRNA Symbols:
miR-222
|
| Accession number:
|
| chromosome Location:
|
| Expression pattern:
Downreguation
|
| High-throughput experiment methods:
|
| Low-throughput experiment methods:
RT-PCR,etal
|
| Targets of ncRNA:
HDAC-4
|
| Detection methods for targets:
Bioinformatics analysis, Luciferase reporter assay, Western blot,RT-PCR
|
| Description the function of ncRNA:
miR-222 may be involved in cartilage destruction by targeting HDAC-4 and regulating MMP-13 level.
|
| Year:
2014
|
| Title:
MicroRNA-222 regulates MMP-13 via targeting HDAC-4 during osteoarthritis pathogenesis
|
| External Link:
Ensembl Link
;
HGNC Link
|
