| PMID:
26774733
|
| Subject&Disease:
Osteoarthritis
|
| Sample:
Cartilage; Primary mouse chondrocytes; Cell line (ATDC5)
|
| Species:
Homo sapiens/Mus musculus
|
| ncRNA Category:
miRNA
|
| ncRNA Symbols:
miR-320
|
| Accession number:
null
|
| chromosome Location:
null
|
| Expression pattern:
Downreguation
|
| High-throughput experiment methods:
null
|
| Low-throughput experiment methods:
RT-PCR,etal
|
| Targets of ncRNA:
MMP-13
|
| Detection methods for targets:
Bioinformatics analysis, Luciferase reporter assay, RT-PCR
|
| Description the function of ncRNA:
Cartilage development and homeostasis are influenced by miR-320, which directly targets MMP-13 and regulates chondrogenesis and the IL-1β-stimulated catabolic effect in mouse chondrocytes.
|
| Year:
2016
|
| Title:
MicroRNA-320 regulates matrix metalloproteinase-13 expression in chondrogenesis and interleukin-1β-induced chondrocyte responses
|
| External Link:
Ensembl Link
;
HGNC Link
|
