| PMID:
28214854
|
| Subject&Disease:
Neuropathic pain
|
| Sample:
Spinal dorsal horn; Cell line(PC12 cell)
|
| Species:
Rattus norvegicus
|
| ncRNA Category:
miRNA
|
| ncRNA Symbols:
miR-183
|
| Accession number:
|
| chromosome Location:
|
| Expression pattern:
Upregulation
|
| High-throughput experiment methods:
|
| Low-throughput experiment methods:
RT-PCR,etal
|
| Targets of ncRNA:
mTOR and VEGF
|
| Detection methods for targets:
Bioinformatics analysis, Luciferase reporter assay,Western blot,RT-PCR
|
| Description the function of ncRNA:
The inhibition of mTOR or VEGF receptors can significantly relieve neuropathic pain, and the upregulation of miR-183 can suppress AMPA receptors by inhibiting mTOR/VEGF pathway.
|
| Year:
2017
|
| Title:
MicroRNA-183 Suppresses Neuropathic Pain and Expression of AMPA Receptors by Targeting mTOR/VEGF Signaling Pathway
|
| External Link:
Ensembl Link
;
HGNC Link
|
