Help & FAQs

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  • 01 Get an overview of elncVarReg from the Home page.
  • The Home page is displayed in Figure 1-1:
    1 Main functions of the web resource are provided in menu bar form (boxed in red).
    2 A quick search for regulatory model among SNP, elncRNA and PCG.
    3 A schematic diagram of the regulatory model in elncVarReg.
    4 A quick view of functions in elncVarReg.

    Figure 1-1

  • 02 How to search the regulatory model among SNPs, elncRNAs and PCGs?
  • In the model search section, users can get the regulatory relationship among SNPs, elncRNAs and PCGs.
    1 Input SNP by rsID.
    2 Input elncRNA by Ensembl gene id or symbol.
    3 Input PCG by Ensembl gene id or symbol.
    4 Select the regulatory model of interest.
    5 Click the Search button to get the result page.
    6 Click to select the corresponding result table.
    7 Click to download the results.

    Figure 2-1

  • 03 How to browse your interest SNP, elncRNA and PCG in Genome Browser?
  • In the genome browser section, users can browse genomic positions of SNP, elncRNA and PCG.
    1 Input the interested rsID, elncRNA/PCG Ensembl gene id or symbol, or genomic region.
    2 Click Search button to get detailed information in Genome Browser.

    Figure 3-1

  • 04 How to download regulatory models and R language code of maximum likelihood estimation in elncVarReg?
  • 1 Users can download dataset of interest by clicking the corresponding link.
    2 Download R code of maximum likelihood estimation (MLE) to predict the regulatory relationship of SNP-elncRNA-PCG triplets of interest in local computer.

    Figure 4-1