| Details |
| Disease Name | Neuroblastoma |
| Nocoding RNA Name | CAI2 |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | qRT-PCR,transfection etc. |
| Target | N/A |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 25028366 |
| Year | 2014 |
| Detail Description | CAI2 is a single-exon gene with a poly A signal located in but independent of the p16/ARF exon 3. CAI2 is expressed at very low levels in normal tissue, but is highly expressed in most tumor cell lines with an intact 9p21 locus. Concordant expression of CAI2 with p16 and ARF in normal tissue along with the ability of CAI2 to induce p16 expression suggested that CAI2 may regulate p16 and/or ARF. In neuroblastoma cells transformed by serial passage in vitro, leading to more rapid proliferation, CAI2, p16, and ARF expression all increased dramatically. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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