Details
Disease Name Neuroblastoma
Nocoding RNA Name CASC15-S
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods Taqman RT-PCR,siRNA,RNA Fluorescent In situ hybridization etc.
Target N/A
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 26100672
Year 2015
Detail Description Low-level expression of a short CASC15 isoform (CASC15-S) associated highly with advanced neuroblastoma and poor patient survival. In human neuroblastoma cells, attenuating CASC15-S increased cellular growth and migratory capacity. Gene expression analysis revealed downregulation of neuroblastoma-specific markers in cells with attenuated CASC15-S, with concomitant increases in cell adhesion and extracellular matrix transcripts.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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