| Disease Name |
Glioma |
| Nocoding RNA Name |
ECONEXIN |
| Expression Pattern |
up-regulated |
| Species |
Homo sapiens |
| Detection Methods |
qRT-PCR,Western Blot,microarray,Luciferase Reporter Assay etc. |
| Target |
TOP2A |
| Tissue |
surgically resected glioma samples |
| Treatment |
N/A
|
| PubMed ID |
28368417 |
| Year |
2017 |
| Detail Description |
Expressions of ECONEXIN and C130071C03Rik were significantly upregulated in both human and mouse glioma tissues. Moreover, the expression of C130071C03Rik was upregulated even in precancerous conditions and markedly increased during glioma progression. Functional analysis of ECONEXIN in glioma cell lines, U87 and U251, showed it was dominantly located in the cytoplasm and interacted with miR-411-5p via two binding sites within ECONEXIN. |
|