Details
Disease Name Glioma
Nocoding RNA Name ECONEXIN
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods qRT-PCR,Western Blot,microarray,Luciferase Reporter Assay etc.
Target TOP2A
Tissue surgically resected glioma samples
Treatment N/A
PubMed ID 28368417
Year 2017
Detail Description Expressions of ECONEXIN and C130071C03Rik were significantly upregulated in both human and mouse glioma tissues. Moreover, the expression of C130071C03Rik was upregulated even in precancerous conditions and markedly increased during glioma progression. Functional analysis of ECONEXIN in glioma cell lines, U87 and U251, showed it was dominantly located in the cytoplasm and interacted with miR-411-5p via two binding sites within ECONEXIN.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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