| Details |
| Disease Name | Glioma |
| Nocoding RNA Name | H19 |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | Quantitative RT-PCR,Luciferase Reporter Assay,Western Blot etc. |
| Target | N/A |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 24466011 |
| Year | 2014 |
| Detail Description | we found increased H19 in high grade gliomas. H19 depletion via siRNA inhibited invasion in glioma cells. Further, we found H19 positively correlated with its derivate miR-675 expression and reduction of H19 inhibited miR-675 expression. Bioinformatics and luciferase reporter assays showed that miR-675 modulated Cadherin 13 expression by directly targeting the binding site within the 3' UTR. Finally, introduction of miR-675 abrogated H19 knockdown-induced cell invasion inhibition in glioma cells. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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