| Details |
| Disease Name | Glioma |
| Nocoding RNA Name | H19 |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | qPCR etc. |
| Target | N/A |
| Tissue | human glioma cell lines U251 and U87 |
| Treatment | N/A |
| PubMed ID | 27981546 |
| Year | 2016 |
| Detail Description | LncRNA H19 was overexpressed in glioma tissue and cell lines. LncRNA H19 was negatively associated with patient survival time. In cell culture experiments,silencing of lncRNA H19 diminished proliferation of glioma cell lines. These effects of lncRNA H19 appeared to be intermediated by miR-675. The latter was overexpressed in glioma tissue and was negatively associated with patient survival.Supporting the involvement of miR-675, its antagomir decreased proliferation of glioma cell lines, whereas its mimic increased proliferation of NHA cells. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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