Details
Disease Name Huntington Disease
Nocoding RNA Name HAR1
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods chromatin immunoprecipitation(ChIP)-sequencing,RT-PCR,Luciferase Reporter Assay etc.
Target REST
Tissue brain
Treatment N/A
PubMed ID 20179156
Year 2010
Detail Description we use a genomic strategy to search for candidate lncRNAs in HD. We show that the neural RNA human accelerated region 1 (HAR1) is repressed by REST, and its level is significantly reduced in the brains of human patients.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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