Details
Disease Name Glioblastoma
Nocoding RNA Name HOTAIR
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods Helicos single molecule sequencing,RT-qPCR etc.
Target N/A
Tissue glioblastoma cell lines
Treatment I-BET151
PubMed ID 26111795
Year 2015
Detail Description I-BET151 induced a statistically significant up-regulation of GBM down-regulated lncRNAs including MEG3, NEAT1 (nuclear paraspeckle assembly transcript,and DGCR5. By contrast, this treatment yielded downregulation of GBM up-regulated lncRNAs HOTAIRM1, TUG1(taurine up-regulated 1), and H19 (imprinted maternally expressed transcript).

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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