| Details |
| Disease Name | Ependymoma |
| Nocoding RNA Name | HOTAIR |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | nanoString etc. |
| Target | N/A |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 25085602 |
| Year | 2014 |
| Detail Description | Results indicate that in ATRTs, medulloblastomas, and juvenile pilocytic astrocytomas (JPAs), the HOTAIR and HOXC genes are highly expressed; however, HOXD8-10 genes are not silenced. In ependymomas, there is low expression of the HOXC, HOTAIR, and HOXD8-10 genes.HOX genes are also known to be associated with long noncoding RNAs (lncRNAs) such as HOTAIR, which induces transcriptional silencing of the HOXD locus by recruiting polycomb repressive complex 2 to the HOXD locus. |
NSDNA: The Nervous System Disease NcRNAome Atlas
Contact wanglh211@163.com for inquiries and feedback
© All right reserved 2016