| Disease Name |
Glioma |
| Nocoding RNA Name |
HOTAIR |
| Expression Pattern |
up-regulated |
| Species |
Homo sapiens |
| Detection Methods |
qRT-PCR,Western Blot etc. |
| Target |
PDCD4 |
| Tissue |
human astrocyte HA cell line,The human glioma cell lines U251,U87, LN-18 and H4 |
| Treatment |
N/A
|
| PubMed ID |
28105224 |
| Year |
2016 |
| Detail Description |
A high density of histone 3 lysine 27 trimethylation on the promoter of PDCD4 was associated with the long non-coding RNA, homeobox transcript antisense RNA(HOTAIR). The expression of HOTAIR was significantly increased in glioma cells compared with normal cells, and it exerted its function in a polycomb repressive complex 2-dependent manner. |
|