Details
Disease Name Glioma
Nocoding RNA Name HOTAIR
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods qRT-PCR,Western Blot etc.
Target PDCD4
Tissue human astrocyte HA cell line,The human glioma cell lines U251,U87, LN-18 and H4
Treatment N/A
PubMed ID 28105224
Year 2016
Detail Description A high density of histone 3 lysine 27 trimethylation on the promoter of PDCD4 was associated with the long non-coding RNA, homeobox transcript antisense RNA(HOTAIR). The expression of HOTAIR was significantly increased in glioma cells compared with normal cells, and it exerted its function in a polycomb repressive complex 2-dependent manner.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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