| Details |
| Disease Name | Glioma |
| Nocoding RNA Name | MALAT1 |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | Real-time PCR etc. |
| Target | N/A |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 25613066 |
| Year | 2015 |
| Detail Description | lncRNA MALAT1 expression was increased in glioma tissues compared with paired adjacent brain normal tissues (P < 0.001). Furthermore, lncRNA MALAT1 was associated significantly with WHO grade (I-II vs. III-IV; P = 0.007) and tumor size (< 3 cm vs. T >/= 3 cm; P = 0.008). However, lncRNA MALAT1 expression was not associated significantly with age (<45 vs. >/= 45, P = 0.343), gender (female vs. male, P = 0.196), family history of cancer (yes vs. no, P = 0.665), and tumor location (supratentorial vs. infratentorial, P = 0.170). Moreover, the level of lncRNA MALAT1 expression was markedly correlated with the glioma patients' overall survival (P < 0.001). Multivariate analysis suggested that increased lncRNA MALAT1 expression was a poor independent prognostic predictor for glioma patients. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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